Estrogens - Plural
When we discuss sex hormones, and often when we read about sex hormones, we see three words: estrogen, progesterone, and testosterone.
Rather than viewing these hormones as individual entities, we ought to consider them as a collective. Each sex hormone belongs to a group of steroid hormones that are chemically related and cholesterol-based, yet they produce notably different effects on the body.
Ladies and Gentlemen, The Estrogens
I was completely unaware of the three estrogens before I took my menopause coaching certification. My textbook describes the three estrogens as follows:
Estrone or E1
Estradiol or E2
Estriol or E3
In pre-menopausal, non-pregnant women, estradiol (E2) serves as the main hormone. It sustains the endometrium and stimulates ovulation, primarily produced by the ovarian follicle. When "estrogen" is mentioned as a single hormone, it usually refers to estradiol.
Throughout pregnancy, estriol (E3) experiences a significant rise and is crucial for preserving the placenta. Besides being created by the placenta, it is also generated in the ovaries, liver, and other peripheral tissues. Estriol is considered a weak and less biologically potent form of estrogen.
In menopause, estrone (E1) becomes the dominant hormone. Known as a weak estrogen, estrone is five times less potent than estradiol. After menopause, estrone remains the primary estrogen since ovarian follicles stop producing estradiol. It is mainly produced by adipose tissue, although other tissues also contribute to its production.
While this information may not seem important right now, as we age and progress through the various stages of our cycle, having more knowledge about our reproductive system will better prepare us for changes and enhance our communication of concerns to healthcare professionals. By staying informed, we empower ourselves to navigate these transitions with confidence and ease.
(2023). Menopause Coaching Specialist Certification textbook - GGS Academy. Girls Gone Strong.